Searchable abstracts of presentations at key conferences in endocrinology

ea0090p254 | Thyroid | ECE2023

Endocrine adverse events associated with immune checkpoint inhibitors - A case series

Anne-Marie Stefan Andreea , Iulia-Florentina Burcea , Roxana Ioana Dumitriu , Ramona Dobre , Nicoleta Baculescu , Ionela Baciu , Radian șerban , Cristina Căpățină , Trifanescu Raluca , Poiana Catalina

Background: Immune checkpoint inhibitors (ICIs) are a novel group of drugs, used for treatment of various types of malignancies. The receptors cytotoxic T-lymphocyte antigen-4 (CTLA-4) and programmed cell death protein-1 (PD-1) or its ligand (PDL-1) are targeted by those inhibitors. They are associated with immune-related adverse events (irAEs). Endocrinopathies are the most frequent irAEs with a prevalence of approximately 10%. Case study: We retrospect...